• 介绍：

   Colistin是一种多肽抗生素，其通过与革兰氏阴性细菌的外细胞膜中的脂多糖和磷脂结合来抑制革兰氏阴性细菌。

• 熔点： 200~220℃

• 比旋光度： -63~-73º

• 外观： 白色至类白色粉末

• 溶解性： H2O  :  50  mg/mL  (35.70  mM;  Need  ultrasonic)
  
  DMSO  :  <  1  mg/mL  (insoluble  or  slightly  soluble)

• 储存条件： 2-8℃

• 用途： 本品仅供科研，不得用于其它用途。

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 11. [6.7] Chao Ma et al."Paeonol potentiates colistin efficacy against K. pneumoniae by promoting membrane disruption and oxidative damage."PHYTOMEDICINE.2024 Sep;:156061

• 10. [5.3] Qiushuang Sheng et al."Novel functions of o-cymen-5-ol nanoemulsion in reversing colistin resistance in multidrug-resistant Klebsiella pneumoniae infections."BIOCHEMICAL PHARMACOLOGY.2024 Jun;:116384

• 9. [IF=5.7] Shiyuan Wang et al."Impact of CRAMP-34 on Pseudomonas aeruginosa biofilms and extracellular metabolites."Frontiers in Cellular and Infection Microbiology.2023; 13: 1295311

• 8. [5.295] Kuan Gu et al."Wogonin attenuates the pathogenicity of Streptococcus pneumoniae by double-target inhibition of Pneumolysin and Sortase A."JOURNAL OF CELLULAR AND MOLECULAR MEDICINE.2023 Feb;:

• 7. [5.895] Qiushuang Sheng et al."Naringenin Microsphere as a Novel Adjuvant Reverses Colistin Resistance via Various Strategies against Multidrug-Resistant Klebsiella pneumoniae Infection."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2022;XXXX(XXX):XXX-XXX

• 6. [IF=6.069] Qian Qiu et al."Colistin Crosslinked Gemcitabine Micelles to Eliminate Tumor Drug Resistance Caused by Intratumoral Microorganisms."BIOCONJUGATE CHEMISTRY.2022;XXXX(XXX):XXX-XXX

• 5. [IF=4.396] Gengqi Liu et al."A new self-immolative colistin prodrug with dual targeting functionalities and reduced toxicity for the treatment of intracellular bacterial infections."JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

• 4. Chen, Bo-Chen, et al. "Phenanthrene antibiotic targets bacterial membranes and kills Staphylococcus aureus with a low propensity for resistance development." Frontiers in microbiology 9 (2018): 1593.https://doi.org/10.3389/fmicb.2018.01593

• 3. 周晴. 副溶血弧菌类脂A结构分析及相关基因研究[D].江南大学,2020.

• 2. 岑道机, 麦嘉琳, 周毓源,等. 广东鹅场大肠杆菌耐药状况及blaCTX-M基因的传播特征[J]. 中国畜牧兽医, 2020, 047(005):1571-1582.

• 1. 王宏刚, 张伟, 朱维铭,等. 多黏菌素E诱导肠道菌群失调对肠屏障功能和细菌易位的影响[J]. 肠外与肠内营养, 2012, 019(002):102-106.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *