• 介绍： GW9662是一种选择性PPAR拮抗剂，作用于PPARγ，IC50为3.3 nM，作用于PPARγ比作用于PPARα和PPARδ选择性强100到1000倍。

• 熔点： 171-175℃

• 溶解性： Soluble  in  DMSO  (26  mg/ml),  methanol,  100%  ethanol  (10  mg/ml),  DMF  (~35  mg/ml),  and  1:2  DMF  :  PBS  (PH=7.2)  (~0.5  mg/ml).  Insolub

• 储存条件： 2-8℃

• 用途： A selective, irreversible, and effective PPARγ antagonist that also acts as a FXR and PXR agonist.

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 5. [3.8] Peiyu Xue et al."PPARγ-mediated amelioration of lipid metabolism abnormality by kaempferol."ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS.2024 Nov;761:110154

• 4. [3.5] Guangjie Zhang et al."Oleanolic acid attenuates obesity through modulating the lipid metabolism in high-fat diet-fed mice."Food Science & Nutrition.2024 Aug;:

• 3. [3.8] Zilong Zhang et al."Bivalent affinity binding-inspired PPARγ immobilization with selective conformation and improved ligand-binding activity."JOURNAL OF CHROMATOGRAPHY A.2024 Aug;1730:465141

• 2. [IF=3.4] Zhang Ningzhi et al."PPARγ Agonist Rosiglitazone and Antagonist GW9662: Antihypertensive Effects on Chronic Intermittent Hypoxia-Induced Hypertension in Rats."Journal of Cardiovascular Translational Research".2024 Feb;:1-13

• 1. [IF=5.279] Jing Zhou et al."Ginsenoside F2 Suppresses Adipogenesis in 3T3-L1 Cells and Obesity in Mice via the AMPK Pathway."J Agr Food Chem. 2021;69(32):9299–9312

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *