• 介绍： Nintedanib (BIBF 1120)是一种有效的三重血管激酶抑制剂，对VEGFR1/2/3， FGFR1/2/3和PDGFRα/β均有抑制作用，其IC50分别为34 nM/13 nM/13 nM， 69 nM/37 nM/108 nM和59 nM/65 nM。

• 溶解性： DMSO  6  mg/mL  Water  <1  mg/mL  Ethanol  3  mg/mL

• 储存条件： -20℃

• 用途： BIBF1120 is a potent kinase inhibitor found to affect VEGF, PDGF, and FGF receptors.

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 7. [3.4] Liu Shuyin et al."Preparation, Characterization and Evaluation of Nintedanib Amorphous Solid Dispersions with Enhanced Oral Bioavailability."AAPS PHARMSCITECH.2024 Aug;25(6):1-13

• 6. [IF=7.9] Yang Ruan et al."The Dual Role of 20(S)-protopanaxadiol in Alleviating Pulmonary Fibrosis through the Gut-Lung Axis."PHYTOMEDICINE".2024 May;:155699

• 5. [IF=5.1] Hong Li et al."Qingkailing granule alleviates pulmonary fibrosis by inhibiting PI3K/AKT and SRC/STAT3 signaling pathways."BIOORGANIC CHEMISTRY".2024 Mar;:107286

• 4. [IF=4.927] Sijie Wei et al."Isolation, Characterization, and Anti-Idiopathic Pulmonary Fibrosis Activity of a Fucoidan from Costaria costata."MOLECULES.2023 Jan;28(11):4343

• 3. [5.735] Guo-qing Ren et al."Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways."Journal of Ginseng Research.2023 Jan;:

• 2. [IF=4.36] Zhenghua Wu et al."Schisandrol A, the main active ingredient of Schisandrae Chinensis Fructus, inhibits pulmonary fibrosis through suppression of the TGF-β signaling pathway as revealed by UPLC-Q-TOF/MS, network pharmacology and experimental verification.

• 1. [IF=7.79] Xin Chang et al."Nanoengineered immunosuppressive therapeutics modulating M1/M2 macrophages into the balanced status for enhanced idiopathic pulmonary fibrosis therapy."Nanoscale. 2020 Apr;12(16):8664-8678

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *