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• 产品描述： INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment.

• 靶点： Apoptosis;Microtubule Associated;Apoptosis;MicrotubuleAssociated

• 细胞实验： Standard XTT assays with a four-day drug treatment procedure are performed to measure the dose-dependent cytotoxicity of INH analogs in cultured cells. Triplicate sets are measured and compiled for final data presentation. The assay is performed by using a commercial kit following the instructions. In principle, cells are plated on 96-well dishes one day before the drug treatment, followed by drug treatment on day 2 and XTT assay on day 5 after drug addition. The absorption at 595 nm is measured with a plate reader and converted to cell survival percentages in comparison to mock treated groups.(Only for Reference)

• 参考文献：
  1. Qiu XL, et al. J Med Chem. 2009, 52(6), 1757-1767.

• 溶解性： Soluble  in  DMSO、Ethanol

• 保存条件： -20℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	3.102 ml	15.508 ml	31.015 ml
  5 mM	0.62 ml	3.102 ml	6.203 ml
  10 mM	0.31 ml	1.551 ml	3.102 ml
  50 mM	0.062 ml	0.31 ml	0.62 ml

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *