| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 南京 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S80161-5mg |
99.90% | ￥120.00 |
>10 | - | - | - | - |
|
S80161-10mg |
99.90% | ￥200.00 |
>10 | - | - | - | - |
|
S80161-25mg |
99.90% | ￥380.00 |
>10 | - | - | - | - |
|
S80161-50mg |
99.90% | ￥640.00 |
>10 | - | - | - | - |
|
S80161-100mg |
99.90% | ￥860.00 |
>10 | - | - | - | - |
|
S80161-200mg |
99.90% | ￥1360.00 |
>10 | - | - | - | - |
|
S80161-1g |
99.90% | ￥2800.00 |
>10 | - | - | - | - |
|
| 产品描述： | Biapenem is a 1-beta-methylcarbapenem antibiotic with a wide range of antibacterial activity. Biapenem has similar antibacterial activity to that of imipenem, but is more stable against human renal dehydropeptidase-I and with less neurotoxicity. | ||||||||||||||||||||
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| 靶点： | Antibacterial;Antibiotic | ||||||||||||||||||||
| 体外研究： | Biapenem has activity comparable to those of Imipenem and Meropenem against all groups of anaerobes with MICs for 90% of the strains tested of 0.06 to 2 mg/mL. Biapenem is more active than ampicillin-sulbactam, ticarcillin-clavulanate, piperacillin, cefoxitin, cefotaxime, and ceftriaxone. Biapenem is also active against all of the B. capillosus, Prevotella, Clostridium, and Eubacterium strains and anaerobic cocci tested.Biapenem shows broad antibacterial activity against both Gram-positive and Gram-negative clinical isolates.Biapenem is found to be approximately as active as imipenem, inhibiting 90% of isolates of most species at concentrations within one dilution of the MIC of imipenem for 90% of the isolates. | ||||||||||||||||||||
| 体内研究： | Biapenem results in significantly fewer viable bacteria than in the lungs of control mice. Biapenem prevents the progression of lung inflammation, including alveolar neutrophil infiltration and hemorrhage. Biapenem significantly prolongs survival and reduces the number of viable bacteria in a murine model of VAP caused by P. aeruginosa. | ||||||||||||||||||||
| 参考文献： | 1. Malanoski GJ, et al. In vitro activity of biapenem against clinical isolates of gram-positive and gram-negative bacteria. Antimicrob Agents Chemother, 1993, 37(9), 22009-22016. 2. Hara T, et al. [Antibacterial activity of biapenem against recent clinical isolates]. Jpn J Antibiot, 2003, 56(2), 138-141. 3. Aldridge KE, et al. In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes. Antimicrob Agents Chemother, 1994, 38(4), 889-893. 4. Yamada K, et al. In vitro activity of biapenem (L-627), a new carbapenem, against anaerobes. J Infect Chemother, 2012, 18(4), 472-478. | ||||||||||||||||||||
| 溶解性： | Soluble in H2O | ||||||||||||||||||||
| 保存条件： | 2-8℃,避光 | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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