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• 产品描述： Molsidomine is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO) upon decay as the actual vasodilating compound.

• 靶点： NOD

• 体内研究：
  Molsidomine (50, 100, 250 μg/kg) reduces coronary flow while the coronary resistance remains unaffected by molsidomine. Molsidomine decreases myocardial oxygen consumption. Heart rate and contractility remains unchanged by molsidomine. Stroke volume and cardiac output fall after molsidomine. The fall in blood pressure after molsidomine follows the reduction in cardiac output as sequel of lowered preload and venous return to the heart

• 参考文献：
  1.Volker B. Fiedler, et al. Naunyn-Schmiedeberg's Archives of Pharmacology. 1981, 317(1):71-77.

• 溶解性： Ethanol:21  mg/mL(86.7  mM)    DMSO:45  mg/mL  (185.8  mM)    H2O:9  mg/mL  (37.15  mM)

• 保存条件： 2-8°C,避光

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	4.128 ml	20.642 ml	41.283 ml
  5 mM	0.826 ml	4.128 ml	8.257 ml
  10 mM	0.413 ml	2.064 ml	4.128 ml
  50 mM	0.083 ml	0.413 ml	0.826 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *