S80874 |
Pergolide Mesylate |
源叶(MedMol) | 99% |
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- 产品描述: Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research
- 靶点: D2 Receptor;D1 Receptor;DopamineReceptor;5-HTReceptor;AdrenergicReceptor
- 体内研究:
Pergolide (0.3 mg/kg; intraperitoneal injection; daily; 11 days) treatment reduces the number of working/reference memory errors a 6-OHDA-induced rat model of Parkinson's disease. Pergolide facilitates spatial memory and improves brain oxidative balance
- 参考文献:
1. S Franks, et al. Effectiveness of pergolide mesylate in long term treatment of hyperprolactinaemia. Br Med J (Clin Res Ed). 1983 Apr 9;286(6372):1177-9. 2. Daniela Uberti, et al. Pergolide protects SH-SY5Y cells against neurodegeneration induced by H(2)O(2). Eur J Pharmacol. 2002 Jan 2;434(1-2):17-20. 3. Alin Ciobica, et al. The effects of pergolide on memory and oxidative stress in a rat model of Parkinson's disease. J Physiol Biochem. 2012 Mar;68(1):59-69.
- 溶解性: DMSO : ≥ 25 mg/mL (60.89 mM)
- 保存条件: -20℃
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 2.435 ml 12.177 ml 24.355 ml 5 mM 0.487 ml 2.435 ml 4.871 ml 10 mM 0.244 ml 1.218 ml 2.435 ml 50 mM 0.049 ml 0.244 ml 0.487 ml
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质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)