S81238 |
WZ4003 |
源叶(MedMol) | 97% |
- 提示:详情请下载说明书。
- 产品描述: WZ4003 is the first potent and highly specific NUAK kinase inhibitor with IC50 of 20 nM/100 nM for NUAK1 (ARK5)/NUAK2, without significant inhibition on other 139 kinases.
- 靶点: NUAK1:20 nM (IC50);NUAK2:100 nM (IC50);AMPK
- 参考文献:
1. Banerjee S, et al. Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. Biochem J. 2014 Jan 1;457(1):215-25. 2. Zhou W, et al. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M. Nature. 2009 Dec 24;462(7276):1070-4
- 溶解性: DMSO : 33.33 mg/mL (67.06 mM; Need ultrasonic)
- 保存条件: -20℃
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 2.012 ml 10.061 ml 20.121 ml 5 mM 0.402 ml 2.012 ml 4.024 ml 10 mM 0.201 ml 1.006 ml 2.012 ml 50 mM 0.04 ml 0.201 ml 0.402 ml
- 注意:部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。
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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)