• 提示：详情请下载说明书。

• 产品描述： NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively.

• 靶点： MAPK

• 细胞实验： Breast cancer cells were seeded in 12-well plates at 2?×?10^3 cells per well, then incubated with Dox alone or Dox with NG25 at indicated concentrations after 72?h and then were cultured in fresh medium without drug.?Two weeks later, cells were fixed and stained with methanol/crystal violet for 10?min, and photographed.?Each experiment was performed in triplicates

• 参考文献：
  1.Wang Z , Zhang H , Shi M , et al. TAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cells[J]. Scientific Reports, 2016, 6:32737. 2.Pauls E , Shpiro N , Peggie M , et al. Essential Role for IKKβ in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells *[J]. Journal of Biological Chemistry, 2012, 287.

• 溶解性： DMSO:100  mg/mL  (186.02  mM)

• 保存条件： -20℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	1.86 ml	9.301 ml	18.602 ml
  5 mM	0.372 ml	1.86 ml	3.72 ml
  10 mM	0.186 ml	0.93 ml	1.86 ml
  50 mM	0.037 ml	0.186 ml	0.372 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *