S82965 |
Mutant IDH1-IN-1 |
源叶(MedMol) | 98% |
- 提示:详情请下载说明书。
- 产品描述: Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.
- 靶点: IDH1;Dehydrogenase; IsocitrateDehydrogenase(IDH)
- 参考文献:
1. Deng G, et al. Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. J Biol Chem. 2015 Jan 9;290(2):762-74.
- 溶解性: Soluble in DMSO
- 保存条件: -20℃
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 2.006 ml 10.028 ml 20.057 ml 5 mM 0.401 ml 2.006 ml 4.011 ml 10 mM 0.201 ml 1.003 ml 2.006 ml 50 mM 0.04 ml 0.201 ml 0.401 ml
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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)