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• 产品描述： DMA trihydrochloride is a fluorescent compound (λex=340 nm, λem=478 nm).

• 靶点： IC50: 3.4 μM (HeLa cell), 5.3 μM (MCF7 cell);Others

• 体外研究：
  The newly synthesized bisbenzimidazole derivatives DMA (6c) is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), breast carcinoma cell line (MCF7) and brain glioma cell line (U87) in comparison to Hoechst. In case of MCF7, the IC50 is observed at 5.3 μM for DMA. The IC50 determined in the case of HeLa is 3.4 μM for DMA

• 参考文献：
  1. Singh M, et al. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles. Eur J Med Chem. 2011 Feb;46(2):659-69.

• 溶解性： Soluble  in  H2O

• 保存条件： -20℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	1.73 ml	8.652 ml	17.303 ml
  5 mM	0.346 ml	1.73 ml	3.461 ml
  10 mM	0.173 ml	0.865 ml	1.73 ml
  50 mM	0.035 ml	0.173 ml	0.346 ml

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *