| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 南京 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
S84628-5mg一口价 |
99.70% | ￥150.00 ￥120.00 |
5 | - | - | - | - |
|
S84628-10mg一口价 |
99.70% | ￥235.00 ￥188.00 |
7 | - | - | - | - |
|
S84628-25mg一口价 |
99.70% | ￥370.00 ￥296.00 |
6 | - | - | - | - |
|
S84628-50mg一口价 |
99.70% | ￥550.00 ￥440.00 |
5 | - | - | - | - |
|
| 产品描述： | Leonurine hydrochloride is an alkaloid isolated from Leonurus artemisia, with anti-oxidative and anti-inflammatory. | ||||||||||||||||||||
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| 靶点： | Autophagy;TLR; Autophagy | ||||||||||||||||||||
| 体内研究： | Leonurine (10 mg/kg/d, p.o.) significantly increases the expressions of PPARγ, LXRα, ABCA1 and ABCG1, and decreases both TG and TC levels in serum of mice. Leonurine hydrochloride (50, 100, 200 mg/kg) improves intracellular lipid accumulation via activating AMPK/SREBP1 pathway, enhances biochemical parameters, reduces hepatic lipoperoxide and increases antioxidant levels in mice. Leonurine (20 mg/kg, p.o.) ameliorates osteoarthritis development in mouse DMM model | ||||||||||||||||||||
| 参考文献： | 1. Jiang T, et al. Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner. Cell Physiol Biochem. 2017;43(4):1703-1717. 2. Zhang L, et al. Novel hepatoprotective role of Leonurine hydrochloride against experimental non-alcoholic steatohepatitis mediated via AMPK/SREBP1 signaling pathway. Biomed Pharmacother. 2018 Dec 7;110:571-581. 3. Hu ZC, et al. Inhibition of PI3K/Akt/NF-κB signaling with leonurine for ameliorating the progression of osteoarthritis: In vitro and in vivo studies. J Cell Physiol. 2018 Nov 11. | ||||||||||||||||||||
| 溶解性： | DMSO : ≥ 31 mg/mL (89.13 mM) H2O : 5 mg/mL (14.38 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存条件： | RT | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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