• 提示：详情请下载说明书。

• 产品描述： Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake.

• 靶点： Adrenergic Receptor;AdrenergicReceptor

• 体内研究：
  In 5 patients with multiple system atrophy, administration of 15 mg/day of amezinium metilsulfate, an adrenergic agent, during 6 months for the treatment of postural hypotension exacerbated post-micturition residuals as compared to that before treatment (178 ml versus 113 ml for a change of 37 %). The reduction ratio of FTBF was significantly increased by amezimium [placebo, 75.9%; amezinium, 85.1%; midodrine, 78.1%]. The infusion rate of noradrenaline producing a half-maximum venoconstriction was significantly decreased by amezinium (placebo, 40.6 ng/min; amezinium, 21.0 ng/min)

• 参考文献：
  1. Harada K, et al. Effect of amezinium metilsulfate on the finger skin vasoconstrictor response to cold stimulation and venoconstrictor response to noradrenaline. Jpn Circ J. 1998 Nov;62(11):824-8. 2. Sakakibara R, et al. Amezinium metilsulfate, a sympathomimetic agent, may increase the risk of urinary retention in multiple system atrophy. Clin Auton Res. 2003 Feb;13(1):51-3.

• 溶解性： Soluble  in  DMSO

• 保存条件： -20°C

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	3.192 ml	15.958 ml	31.915 ml
  5 mM	0.638 ml	3.192 ml	6.383 ml
  10 mM	0.319 ml	1.596 ml	3.192 ml
  50 mM	0.064 ml	0.319 ml	0.638 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *