S86055 |
CID 2011756 |
源叶(MedMol) | 97% |
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- 产品描述: CID 2011756 is an ATP competitive PKD inhibitor, with an IC50 of 3.2 µM for PKD1 in cell free assay, and also shows cellular pan-PKD inhibitory activity against PKD2 and PKD3 (IC50, 0.6 and 0.7 µM, respectively). CID 2011756 also has antitumor activity.
- 靶点: Cellular PKD2:0.6 μM (IC50);Cellular PKD3:0.7 μM (IC50);PKD1:3.2 μM (IC50);Serine/threoninkinase
- 参考文献:
1. Sharlow ER, et al. Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. PLoS One. 2011;6(10):e25134.
- 溶解性: Soluble in DMSO
- 保存条件: RT
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 2.52 ml 12.599 ml 25.197 ml 5 mM 0.504 ml 2.52 ml 5.039 ml 10 mM 0.252 ml 1.26 ml 2.52 ml 50 mM 0.05 ml 0.252 ml 0.504 ml
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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)