• 产品描述： Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations

• 靶点： Apoptosis;Raf;Ras

• 体内研究：
  In vivo administration of oncrasin-1 suppressed the growth of K-ras mutant human lung tumor xenografts by >70% and prolonged the survival of nude mice bearing these tumors, without causing detectable toxicity

• 参考文献：
  1.Guo W , Wu S , Liu J , et al. Identification of a Small Molecule with Synthetic Lethality for K-Ras and Protein Kinase C Iota[J]. Cancer Research, 2008, 68(18):7403-7408. 2.Guo W , Wu S , Wang L , et al. Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1)[J]. Molecular Cancer Therapeutics, 2009, 8(2):441-448.

• 溶解性： Soluble  in  DMSO

• 保存条件： RT

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	3.707 ml	18.537 ml	37.074 ml
  5 mM	0.741 ml	3.707 ml	7.415 ml
  10 mM	0.371 ml	1.854 ml	3.707 ml
  50 mM	0.074 ml	0.371 ml	0.741 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *