• 产品描述： MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production. MHP (Methyl caprooyl tyrosinate) enhances antimicrobial defense and innate immunity

• 靶点： SphK1;S1PReceptor

• 体外研究：
  MHP (50-250 μM for 24 hours) increases CAMP mRNA levels in keratinocytes. MHP (100 μM for 24 hours) increases CAMP protein levels in keratinocytes. Cell Viability Assay Cell Line: Keratinocytes Concentration: 100 μM Incubation Time: 24 hours Result: Increased CAMP protein levels in keratinocytes.

• 参考文献：
  1. Jeong SK, et al. Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. J Dermatol Sci. 2015 Sep;79(3):229-34.

• 溶解性： Soluble  in  DMSO

• 保存条件： -20°C

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	3.409 ml	17.044 ml	34.088 ml
  5 mM	0.682 ml	3.409 ml	6.818 ml
  10 mM	0.341 ml	1.704 ml	3.409 ml
  50 mM	0.068 ml	0.341 ml	0.682 ml

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *