• 产品描述： UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM

• 靶点： IC50: 12 nM (Ferroptosis);Ferroptosis

• 体内研究：
  No toxicity is observed in mice after repeated injections of UAMC-3203 (20 µmol/kg; injected intraperitoneally; daily, over a period of 4 weeks). Animal Model: Wild type mice derived from a Gpx4 fl/fl breeding Dosage: 20 µmol/kg Administration: Injected intraperitoneally; daily, over a period of 4 weeks Result: No toxicity was observed.

• 参考文献：
  1. Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140.

• 溶解性： Soluble  in  DMSO

• 保存条件： -20°C

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	1.968 ml	9.84 ml	19.68 ml
  5 mM	0.394 ml	1.968 ml	3.936 ml
  10 mM	0.197 ml	0.984 ml	1.968 ml
  50 mM	0.039 ml	0.197 ml	0.394 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *