S89049 |
5-羟甲基脱氧尿苷 |
| 源叶(MedMol) | 98% |
- 产品描述： 5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analog. 5-Hydroxymethyl-2'-deoxyuridine inhibits the replication of multiple human leukemia cell lines with IC50 values of 1.7-5.8 μM. 5-Hydroxymethyl-2'-deoxyuridine prolongs the survival of mice carrying L1210 leukemia. 5-Hydroxymethyl-2'-deoxyuridine can be used for the research of cell replication and leukemia
- 靶点： HSV
- 体内研究：
5-Hydroxymethyl-2'-deoxyuridine (0, 5 and 50 mg/kg; i.p.; once) increases the survival of DBA/2 mice carrying L1210 leukemia
- 参考文献：
1. Shiau GT, et al. Synthesis and biological activities of 5-(hydroxymethyl, azidomethyl, or aminomethyl)-2'-deoxyuridine and related 5'-substituted analogues. J Med Chem. 1980 Feb;23(2):127-33. 2. Kahilainen LI, et al. 5-Hydroxymethyl-2'-deoxyuridine. Cytotoxicity and DNA incorporation studied by using a novel [2-14C]-derivative with normal and leukemic human hematopoietic cells. Acta Chem Scand B. 1985;39(6):477-84. 3. JA Vilpo, et al. 5-Hydroxymethyl-2′-Deoxyuridine: Studies of Antileukemic Properties in Vitro and in Vivo. Nucleosides and Nucleotides . 1987.
- 溶解性： Soluble in DMSO
- 保存条件： -20℃
- 配置溶液浓度参考：
1mg 5mg 10mg 1 mM 3.873 ml 19.363 ml 38.725 ml 5 mM 0.775 ml 3.873 ml 7.745 ml 10 mM 0.387 ml 1.936 ml 3.873 ml 50 mM 0.077 ml 0.387 ml 0.775 ml
- 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。
输入产品批号：
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)
