• 产品描述：

  PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.

• 靶点： PD-1/PD-L1

• 细胞实验： PDL-1 cpd 10 demonstrated to strongly bind with the PD-L1 protein and challenged it in a co-culture of PD-L1 expressing cancer cells (PC9 and HCC827 cells) and peripheral blood mononuclear cells enhanced antitumor immune activity of the latter.PDL-1 cpd 10 significantly increased interferon γ release and apoptotic induction of cancer cells, with low cytotoxicity in healthy cells.

• 参考文献：
  Interfering with the Tumor–Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors

• 溶解性： Soluble  in  DMSO

• 保存条件： -20℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	2.649 ml	13.247 ml	26.494 ml
  5 mM	0.53 ml	2.649 ml	5.299 ml
  10 mM	0.265 ml	1.325 ml	2.649 ml
  50 mM	0.053 ml	0.265 ml	0.53 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *