- 产品描述: SR15006 is a inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells)
- 靶点: KLF;DNA/RNASynthesis
- 体外研究:
SR15006 (1 μM or 10 μM; DLD-1 CRC cells) causes a significant reduction in the levels of tested cyclins over the course of 72 hours
- 参考文献:
1. Kim J, et al. The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo. Mol Cancer Ther. 2019;18(11):1973-1984.
- 溶解性: Soluble in DMSO
- 保存条件: -20℃,避光
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 2.592 ml 12.958 ml 25.915 ml 5 mM 0.518 ml 2.592 ml 5.183 ml 10 mM 0.259 ml 1.296 ml 2.592 ml 50 mM 0.052 ml 0.259 ml 0.518 ml
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输入产品批号:
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)