• 产品描述： NSC 698600 is a potent PCAF inhibitor, with IC50 of 6.51 µM (PCAF/H31-21). NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells

• 靶点： IC50: 6.51 µM (PCAF/H31-21)

• 体外研究：
  NSC 698600 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells. Cell Proliferation Assay Cell Line: SK-N-SH, HCT116 cells Concentration: 25 µM Incubation Time: 72 h Result: Showed antiproliferative effect to SK-N-SH and HCT116 cells with GI50 of 12.2 µM and growth inhibition of 40%, respectively.

• 参考文献：
  1. Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89.

• 保存条件： -20℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	3.672 ml	18.361 ml	36.722 ml
  5 mM	0.734 ml	3.672 ml	7.344 ml
  10 mM	0.367 ml	1.836 ml	3.672 ml
  50 mM	0.073 ml	0.367 ml	0.734 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *