• 产品描述： NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 value of 15.9 μM for recombinant HAT p300/CBP-associated factor (PCAF). NSC 694623 has antiproliferative activity against certain cancer cells. NSC 694623 can be used for researching anticancer

• 靶点： PCAF: 15.9 μM (IC50);HistoneAcetyltransferase

• 体外研究：
  NSC 694623 has antiproliferative activity against SK-N-SH with an IC50 of 8.93 μM, and inhibits 21% of HCT116 at 25 μM

• 参考文献：
  1. Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89.

• 溶解性： Soluble  in  DMSO

• 保存条件： -20℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	3.516 ml	17.582 ml	35.164 ml
  5 mM	0.703 ml	3.516 ml	7.033 ml
  10 mM	0.352 ml	1.758 ml	3.516 ml
  50 mM	0.07 ml	0.352 ml	0.703 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *