S84184 |
TAS-301 |
源叶(MedMol) | 98% |
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- 产品描述: TAS-301 is an inhibitor of smooth muscle cell migration and proliferation, and inhibits PKC activation induced by PDGF.
- 靶点: PKC
- 体内研究:
TAS-301 (3-100 mg/kg, p.o.) dose-dependently reduces the neointimal thickening and I/M ratio and decreases the level of intimal cells in rats 14 days after balloon injury
- 参考文献:
1. Muranaka Y, et al. TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries. J Pharmacol Exp Ther. 1998 Jun;285(3):1280-6. 2. Sasaki E, et al. TAS-301 blocks receptor-operated calcium influx and inhibits rat vascular smooth muscle cell proliferation induced by basic fibroblast growth factor and platelet-derived growth factor. Jpn J Pharmacol. 2000 Nov;84(3):252-8.
- 溶解性: DMSO : ≥ 38 mg/mL (106.32 mM)
- 保存条件: RT
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 2.798 ml 13.99 ml 27.98 ml 5 mM 0.56 ml 2.798 ml 5.596 ml 10 mM 0.28 ml 1.399 ml 2.798 ml 50 mM 0.056 ml 0.28 ml 0.56 ml
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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)