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• 产品描述： Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry

• 靶点： Coccidia;Parasite

• 体内研究：
  Toltrazuril sulfone (10-20 mg/kg; p.o.; daily; for 10 days) is effective in preventing and treating toxoplasmosis in mice Animal Model: Female CD-1 mice Dosage: 10 mg/kg, 20 mg/kg Administration: Oral administration, daily, for 10 days Result: Prevented and protected mice from toxoplasmosis.

• 参考文献：
  1. Sheila M Mitchell, et al. The effects of ponazuril on development of apicomplexans in vitro. J Eukaryot Microbiol. May-Jun 2005;52(3):231-5. 2. Sheila M Mitchell, et al. Efficacy of ponazuril in vitro and in preventing and treating Toxoplasma gondii infections in mice. J Parasitol. 2004 Jun;90(3):639-42.

• 溶解性： Soluble  in  DMSO

• 保存条件： 2-8℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	2.186 ml	10.932 ml	21.864 ml
  5 mM	0.437 ml	2.186 ml	4.373 ml
  10 mM	0.219 ml	1.093 ml	2.186 ml
  50 mM	0.044 ml	0.219 ml	0.437 ml

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *