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T90150

5-氯-8-羟基-7-碘喹啉

源叶 10mM in DMSO
  • 英文名:
  • 5-Chloro-8-hydroxy-7-iodoquinoline
  • 别名:
  • 奎諾仿;Clioqinol; 5-Chloro-8-hydroxy-7-iodoquinoline; Iodochlorhydroxyquin;
  • CAS号:
  • 130-26-7
  • 分子式:
  • C9H5ClINO
  • 分子量:
  • 305.5
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源叶 T90150-1ml 10mM in DMSO ¥205.00元 6 - - - EA 加入购物车
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  • 介绍: 金属螯合剂和离子载体;Metal chelator and ionophore;Clioquinol is a member of the hydroxyquinoline family which inhibits certain enzymes related to DNA replication. Clioquinol is a metal chelating ligand which displays protective effects in various neurodegenerative states as well as being a component in antifungal and antiprotozoal agents. It has been shown to modulate amyloid beta-peptide accumulation via upregulation of metalloprotease activity. When co-administered with vitamin B12, Clioquinol rescues lead-induced impairments of synaptic plasticity in an animal models. In recent animal studies Clioquinol has shown to reverse the progression of Parkinson's, Alzheimer's, and Huntington's diseases. Clioquinol has been observed to induce apoptosis in human cancer cell lines by generating free zinc in lysosomes.;Clioquinol is a member of the hydroxyquinoline family which inhibits certain enzymes related to DNA replication. Clioquinol is a metal chelating ligand which displays protective effects in various neurodegenerative states as well as being a component in antifungal and antiprotozoal agents. It has been shown to modulate amyloid beta-peptide accumulation via upregulation of metalloprotease activity. When co-administered with vitamin B12, Clioquinol rescues lead-induced impairments of synaptic plasticity in an animal models. In recent animal studies Clioquinol has shown to reverse the progression of Parkinson's, Alzheimer's, and Huntington's diseases. Clioquinol has been observed to induce apoptosis in human cancer cell lines by generating free zinc in lysosomes.A metal chelating ligand that inhibits certain enzymes related to DNA replication.
  • 储存条件: 避光,-80℃(运输条件:冰袋低温运输)
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