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产品描述： INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment. |
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靶点：
Apoptosis;Microtubule Associated;Apoptosis;MicrotubuleAssociated |
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细胞实验：
Standard XTT assays with a four-day drug treatment procedure are performed to measure the dose-dependent cytotoxicity of INH analogs in cultured cells. Triplicate sets are measured and compiled for final data presentation. The assay is performed by using a commercial kit following the instructions. In principle, cells are plated on 96-well dishes one day before the drug treatment, followed by drug treatment on day 2 and XTT assay on day 5 after drug addition. The absorption at 595 nm is measured with a plate reader and converted to cell survival percentages in comparison to mock treated groups.(Only for Reference) |
参考文献：
1. Qiu XL, et al. J Med Chem. 2009, 52(6), 1757-1767. |
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溶解性：
Soluble in DMSO、Ethanol |
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保存条件：
-20℃ |
配置溶液浓度参考：
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1mg |
5mg |
10mg |
| 1 mM |
3.102 ml |
15.508 ml |
31.015 ml |
| 5 mM |
0.62 ml |
3.102 ml |
6.203 ml |
| 10 mM |
0.31 ml |
1.551 ml |
3.102 ml |
| 50 mM |
0.062 ml |
0.31 ml |
0.62 ml |
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| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
北京