| 货号 | 规格 | 价格 | 上海 | 北京 | 武汉 | 南京 | 购买数量 |
|---|---|---|---|---|---|---|---|
S80075-1mg |
99.7% | ￥60.00 | 6 | - | - | - |
|
S80075-2mg |
99.7% | ￥80.00 | 7 | - | - | - |
|
S80075-5mg |
99.7% | ￥140.00 | 7 | - | - | - |
|
S80075-10mg |
99.7% | ￥240.00 | 8 | - | - | - |
|
S80075-25mg |
99.7% | ￥480.00 | 5 | - | - | - |
|
S80075-50mg |
≥98% | ￥680.00 | 货期：2-3天 | - | - | - |
|
CP-466722 is a rapidly reversible inhibitor of ATM, with an IC50 of 4.1 μM, and has no effects on PI3K or closely related PI3K-like protein kinase (PIKK) family members.
| 产品描述： | CP-466722 is a rapidly reversible inhibitor of ATM, with an IC50 of 4.1 μM, and has no effects on PI3K or closely related PI3K-like protein kinase (PIKK) family members. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | ATM:4.1 μM (IC50);ATM/ATR | ||||||||||||||||||||
| 参考文献： | 1. Rainey MD, et al. Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation. Cancer Res. 2008 Sep 15;68(18):7466-74. 2. Guo K, et al. Development of a cell-based, high-throughput screening assay for ATM kinase inhibitors. J Biomol Screen. 2014 Apr;19(4):538-46. 3. W?sierska-G?dek J, et al. Interactions Between Ataxia Telangiectasia Mutated Kinase Inhibition, Poly(ADP-ribose) Polymerase-1 Inhibition and BRCA1 Status in Breast Cancer Cells. J Cancer Prev. 2014 Jun;19(2):125-36. | ||||||||||||||||||||
| 溶解性： | DMSO : 1 mg/mL (2.86 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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