产品介绍
BMS-794833 is a VEGFR2 and Met inhibitor extracted from patent WO2009094417, compound example 1; has IC50s of 15 and 1.7 nM, respectively.
产品描述: BMS-794833 is a VEGFR2 and Met inhibitor extracted from patent WO2009094417, compound example 1; has IC50s of 15 and 1.7 nM, respectively.
靶点:
VEGFR2:15 nM (IC50);Met:1.7 nM (IC50);VEGFR;c-Met/HGFR
体内研究:
BMS-794833 is active by greater than 50% tumor growth inhibition for at least one tumor doubling time in the GTL-16 gastric carcinoma model. No toxicity is observed at any of the dose levels when administered once daily for a duration of 14 days
参考文献:
1. WO2009094417
溶解性:
Soluble in DMSO
保存条件:
-20℃
配置溶液浓度参考:
1mg
5mg
10mg
1 mM
2.133 ml
10.665 ml
21.329 ml
5 mM
0.427 ml
2.133 ml
4.266 ml
10 mM
0.213 ml
1.066 ml
2.133 ml
50 mM
0.043 ml
0.213 ml
0.427 ml
注意:
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摩尔浓度计算器
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)