货号	规格	价格	上海	北京	武汉	南京
S80240-5mg	99%	￥80.00 S80240-5mg ￥80.00 现货	8 8	-	-	-
S80240-10mg	99%	￥150.00 S80240-10mg ￥150.00 现货	8 8	-	-	-
S80240-50mg	99%	￥400.00 S80240-50mg ￥400.00 现货	11 >10	-	-	-
S80240-100mg	99%	￥590.00 S80240-100mg ￥590.00 现货	7 7	-	-	-
S80240-500mg	99%	￥1800.00 S80240-500mg ￥1800.00 现货	4 4	-	-	-

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产品介绍

Ciclesonide(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.

产品描述：

Ciclesonide(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.

靶点：

Glucocorticoid Receptor;GlucocorticoidReceptor

细胞实验：

Metabolism of ciclesonide: After initial cultivation, A549 cells are washed five times with 10 ml/dish sterile PBS. An ethanolic stock solution of ciclesonide is diluted 1000-fold with assay medium to generate the initial ciclesonide concentration. The cells are incubated for 1 h in DMEM/0.1% (w/v) BSA (5 ml/dish) containing 0.02 μM ciclesonide as described above in a CO2 incubator. At the end of the incubation period, dishes are washed five times with PBS and incubated for 3, 6, or 24 h at the same conditions in 5 ml/dish fresh medium (DMEM/0.1% (w/v) BSA). At each indicated time point, the medium is removed by aspiration, 5 mM EDTA-4Na/PBS added and dishes are incubated for further 5 min. The cells are detached from the dishes and harvested. Each dish is washed five times with icechilled PBS. (Only for Reference)

参考文献：

1.Nonaka T, et al. BMC Pharmacol. 2007, 7:12. 2.Guo Z, et al. Am J Ther. 2006, 13(6):490-501.

溶解性：

DMSO:54.1 mg/mL (100 mM) Ethanol:54.1 mg/mL (100 mM)

保存条件：

2-8℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	1.849 ml	9.247 ml	18.495 ml
5 mM	0.37 ml	1.849 ml	3.699 ml
10 mM	0.185 ml	0.925 ml	1.849 ml
50 mM	0.037 ml	0.185 ml	0.37 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

Ciclesonide