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Anamorelin 99%

Anamorelin

源叶(MedMol)
S80566
249921-19-5
C31H42N6O3
546.7
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶(MedMol) S80566-5mg 99% ¥306.00元 8 - - -
源叶(MedMol) S80566-10mg 99% ¥476.00元 10 - - -
源叶(MedMol) S80566-25mg 99% ¥1088.00元 10 - - -
源叶(MedMol) S80566-100mg 99% ¥2584.00元 4 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Anamorelin (RC-1291) is a potent ghrelin receptor agonist with EC50 value of 0.74 nM in the FLIPR assay.
产品描述: Anamorelin (RC-1291) is a potent ghrelin receptor agonist with EC50 value of 0.74 nM in the FLIPR assay.
靶点: Ki: 0.7 nM (ghrelin receptor) EC50: 0.74 nM (ghrelin receptor);GHSR
体内研究:
In rats, Anamorelin (ANAM) at an oral dose of 3, 10, or 30 mg/kg once daily significantly increases both food intake and body weight from Day 2 to Day 7 of treatment compared with the vehicle control. The cumulative change in food intake and weight gain increases dose-dependently, and these changes are significant at all dose levels (P<0.05) compared to the control. Administration of Anamorelin at a single oral dose of 3, 10, or 30 mg/kg induces a dose-dependent increase in plasma GH levels and GH AUC0-6h in rats
参考文献:
1. Pietra C, et al. Anamorelin HCl (ONO-7643), a novel ghrelin receptor agonist, for the treatment of cancer anorexia-cachexiasyndrome: preclinical profile. J Cachexia Sarcopenia Muscle. 2014 Dec;5(4):329-37.
溶解性: DMSO  :  ≥  100  mg/mL  (182.92  mM)
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 1.829 ml 9.146 ml 18.292 ml
5 mM 0.366 ml 1.829 ml 3.658 ml
10 mM 0.183 ml 0.915 ml 1.829 ml
50 mM 0.037 ml 0.183 ml 0.366 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

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