| 货号 | 规格 | 价格 | 上海 | 北京 | 武汉 | 南京 | 购买数量 |
|---|---|---|---|---|---|---|---|
| S81238-2mg | 97% | ￥300.00 | 5 | - | - | - |
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| S81238-5mg | 97% | ￥440.00 | 6 | - | - | - |
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| S81238-10mg | 97% | ￥630.00 | 6 | - | - | - |
|
| S81238-25mg | 97% | ￥810.00 | 6 | - | - | - |
|
| S81238-50mg | 97% | ￥1440.00 | 5 | - | - | - |
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| S81238-100mg | 97% | ￥1700.00 | 5 | - | - | - |
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WZ4003 is the first potent and highly specific NUAK kinase inhibitor with IC50 of 20 nM/100 nM for NUAK1 (ARK5)/NUAK2, without significant inhibition on other 139 kinases.
| 产品描述： | WZ4003 is the first potent and highly specific NUAK kinase inhibitor with IC50 of 20 nM/100 nM for NUAK1 (ARK5)/NUAK2, without significant inhibition on other 139 kinases. | ||||||||||||||||||||
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| 靶点： | NUAK1:20 nM (IC50);NUAK2:100 nM (IC50);AMPK | ||||||||||||||||||||
| 参考文献： | 1. Banerjee S, et al. Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases. Biochem J. 2014 Jan 1;457(1):215-25. 2. Zhou W, et al. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M. Nature. 2009 Dec 24;462(7276):1070-4 | ||||||||||||||||||||
| 溶解性： | DMSO : 33.33 mg/mL (67.06 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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