| 产品描述： | Carbidopa ((S)-(-)-Carbidopa), a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa inhibits pancreatic cancer cell and tumor growth |
| 靶点： |
Aryl Hydrocarbon Receptor;Decarboxylase; ArylHydrocarbonReceptor |
| 体内研究： |
Carbidopa also induces nuclear uptake of the AhR, and in vivo studies show that carbidopa at a dose of 1 mg/mouse significantly inhibits tumor growth in athymic nude mice bearing BχPC3 cells as xenografts |
| 参考文献： |
1. Safe S. Carbidopa: a selective Ah receptor modulator (SAhRM). Biochem J. 2017;474(22):3763-3765. Published 2017 Nov 6. 2. Fermaglich J. Treatment of Parkinson's disease with carbidopa, a peripheral decarboxylase inhibitor, and levodopa. Med Ann Dist Columbia. 1974;43(12):587-591. |
| 溶解性： |
DMSO : 10 mg/mL (44.20 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) |
| 保存条件： |
2-8℃ |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
4.42 ml |
22.101 ml |
44.203 ml |
| 5 mM |
0.884 ml |
4.42 ml |
8.841 ml |
| 10 mM |
0.442 ml |
2.21 ml |
4.42 ml |
| 50 mM |
0.088 ml |
0.442 ml |
0.884 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京