| 货号 | 规格 | 价格 | 上海 | 北京 | 武汉 | 南京 | 购买数量 |
|---|---|---|---|---|---|---|---|
S81540-2mg |
99.3% | ￥424.00 | 5 | - | - | - |
|
S81540-5mg |
99.3% | ￥640.00 | 3 | - | - | - |
|
S81540-10mg |
99.3% | ￥1160.00 | 6 | - | - | - |
|
S81540-25mg |
99.3% | ￥2240.00 | 6 | - | - | - |
|
S81540-50mg |
≥98% | ￥3520.00 | 货期：2-3天 | - | - | - |
|
S81540-100mg |
≥98% | ￥4960.00 | 货期：2-3天 | - | - | - |
|
Pluripotin is a dual inhibitor of ERK1 and RasGAP with KDs of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1, RSK2, RSK3, and RSK4 with IC50s of 0.5, 2.5, 3.3, and 10.0 µM, respectively.
| 产品描述： | Pluripotin is a dual inhibitor of ERK1 and RasGAP with KDs of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1, RSK2, RSK3, and RSK4 with IC50s of 0.5, 2.5, 3.3, and 10.0 µM, respectively. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶点： | ERK1:98 nM (Kd);RasGAP:212 nM (Kd);RSK1:0.5 μM (IC50);RSK2:2.5 μM (IC50);RSK3:3.3 μM (IC50);RSK4:10 μM (IC50);ERK; Raf; S6Kinase | ||||||||||||||||||||
| 参考文献： | 1. Chen S, et al. Self-renewal of embryonic stem cells by a small molecule. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17266-71. 2. Mertins SD, et al. A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept. PLoS One. 2013;8(2):e57099. | ||||||||||||||||||||
| 溶解性： | DMSO : 25 mg/mL (45.41 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存条件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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