VBY-825 98%

VBY-825

源叶(MedMol)
S82789
1310340-58-9
C23H29F4N3O5S
535.5521
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶(MedMol) S82789-5mg 98% ¥4200.00元 预计交期:2-3天 - - -
源叶(MedMol) S82789-10mg 98% ¥6600.00元 预计交期:2-3天 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
产品描述: VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
靶点: Cysteine Protease;CysteineProtease
体外研究: VBY-825 is a potent assayed cathepsins inhibitor and its potency against at least one cathepsin, cathepsin S, extends across species relevant for pharmacology studies, specifically mouse. 10 mg/kg/day dose of VBY-825 achieves a trough plasma concentration >200nM, which is well above that required for full inhibition of the intracellular activity of cathepsins B, F, K, L, S and V in both mouse and human cell lines.
参考文献: 1. Elie BT, et al. Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model. Biochimie. 2010 Nov;92(11):1618-24.
溶解性: soluble  in  DMSO
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 1.867 ml 9.336 ml 18.672 ml
5 mM 0.373 ml 1.867 ml 3.734 ml
10 mM 0.187 ml 0.934 ml 1.867 ml
50 mM 0.037 ml 0.187 ml 0.373 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

如何获取质检证书(COA)?
请输入货号和一个与之匹配的批号。
例如:
批号:JS298415 货号:S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

=
×
×

相关产品