货号	规格	价格	上海	北京	武汉	南京	购买数量
S82789-5mg	98%	￥4200.00 S82789-5mg ￥4200.00 2-3天	0 货期：2-3天	-	-	-
S82789-10mg	98%	￥6600.00 S82789-10mg ￥6600.00 2-3天	0 货期：2-3天	-	-	-

产品介绍

VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.

产品描述：

VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.

靶点：

Cysteine Protease;CysteineProtease

体外研究：

VBY-825 is a potent assayed cathepsins inhibitor and its potency against at least one cathepsin, cathepsin S, extends across species relevant for pharmacology studies, specifically mouse. 10 mg/kg/day dose of VBY-825 achieves a trough plasma concentration >200nM, which is well above that required for full inhibition of the intracellular activity of cathepsins B, F, K, L, S and V in both mouse and human cell lines.

参考文献：

1. Elie BT, et al. Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model. Biochimie. 2010 Nov;92(11):1618-24.

溶解性：

soluble in DMSO

保存条件：

-20℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	1.867 ml	9.336 ml	18.672 ml
5 mM	0.373 ml	1.867 ml	3.734 ml
10 mM	0.187 ml	0.934 ml	1.867 ml
50 mM	0.037 ml	0.187 ml	0.373 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

质检证书(COA)

输入产品批号：

如何获取质检证书(COA)?

请输入货号和一个与之匹配的批号。
例如:
批号：JS298415 货号：S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

VBY-825