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S83403

Gamithromycin (ML-1709460)

源叶(MedMol) 98%
  • 英文名:
  • (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-Cmethyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino
  • 别名:
  • 加米霉素;GAMITHROMYCIN;(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-Cmethyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideo
  • CAS号:
  • 145435-72-9
  • 分子式:
  • C40H76N2O12
  • 分子量:
  • 777.038
品牌货号产品规格价格(RMB) 库存(上海) 北京 武汉 南京 数量计量单位 加入购物车...
源叶(MedMol) S83403-5mg 98% ¥240.00元 >10 - - - EA 加入购物车
源叶(MedMol) S83403-10mg 98% ¥360.00元 >10 - - - EA 加入购物车
源叶(MedMol) S83403-50mg 98% ¥1200.00元 >10 - - - EA 加入购物车
源叶(MedMol) S83403-250mg 98% ¥3500.00元 >10 - - - EA 加入购物车
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  • 提示:详情请下载说明书。
  • 产品描述: Gamithromycin is an antimicrobial agent which can inhibit the growth of MmmSC strains B237 and Tan8 with MICs of 0.00012 and 0.00006 μg/mL, respectively.
  • 靶点: MIC: 0.00012 μg/mL (MmmSC strain B237), 0.00006μg/mL (MmmSC strain Tan8);Antibacterial; Antibiotic
  • 体内研究:
    The proportion of foals that recover without the need for a change in treatment is significantly (P<0.048) higher for foals treated with Gamithromycin (GAM) (38 of 40; 95%) or AZM-RIF (39 of 40; 98%) compare to control foals (32 of 41; 78%). The clinical scores, number of abscesses and the abscess scores after 1 and 2 weeks of treatment are significantly lower for foals treated with Gamithromycin (GAM) or AZM-RIF compare to control foals. The WBC count of foals treated with Gamithromycin (GAM) is significantly higher than that of foals treated with AZM-RIF on week 3 of treatment
  • 参考文献:
    1. Mitchell JD, et al. In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. Vet J. 2013 Sep;197(3):806-11. 2. F. Hildebrand, et al. Efficacy of Gamithromycin for the Treatment of Foals with Mild to Moderate Bronchopneumonia. J Vet Intern Med. 2015 Jan-Feb; 29(1): 333–338.
  • 溶解性: DMSO  :  100  mg/mL  (128.69  mM;  Need  ultrasonic)
  • 保存条件: 2-8℃
  • 配置溶液浓度参考:
    1mg 5mg 10mg
    1 mM 1.287 ml 6.435 ml 12.869 ml
    5 mM 0.257 ml 1.287 ml 2.574 ml
    10 mM 0.129 ml 0.643 ml 1.287 ml
    50 mM 0.026 ml 0.129 ml 0.257 ml
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