货号	产品规格	价格(RMB)	库存（上海）	北京	武汉	南京
S83458-10mg	99%	￥180.00 S83458-10mg ￥180.00 现货	10 10	-	-	-
S83458-50mg	99%	￥480.00 S83458-50mg ￥480.00 现货	8 8	-	-	-
S83458-100mg	99%	￥690.00 S83458-100mg ￥690.00 现货	6 6	-	-	-

产品介绍

HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone) is a potent lipophilic phenolic antioxidant. HTHQ has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS) and scavenging ROS to form more stable free radicals

产品描述：

靶点：

ROS;ReactiveOxygenSpecies

体内研究：

HTHQ (50-200 mg/kg; oral administration; for 4 weeks; specific pathogen-free male Sprague Dawley rats) treatment significantly improves liver weight and serum chemistry level. HTHQ reduces hydroxyproline and malondialdehyde level in the liver. HTHQ treatment also reduces fibrotic septa. HTHQ administration shows reduced mRNA level of PDGF (Plateletderived growth factor) , α-SMA (α-smooth muscle actin) and TGF-β (transforming growth factor-β) than DMN-induced hepetic fibrosis animals in the liver tissue

参考文献：

1. Park HJ, et al. 1-O-Hexyl-2,3,5-Trimethylhydroquinone Ameliorates l-DOPA-Induced Cytotoxicity in PC12 Cells. Molecules. 2019 Mar 1;24(5). pii: E867. 2. Jung YR et al. Inhibitory Effect of 1-O-Hexyl-2,3,5-Trimethylhydroquinone on Dimethylnitrosamine-induced Liver Fibrosis in Male SD Rats. Toxicol Res. 2010 Sep;26(3):193-201.

溶解性：

DMSO : 100 mg/mL (423.10 mM; Need ultrasonic)

保存条件：

2-8℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	4.195 ml	20.976 ml	41.952 ml
5 mM	0.839 ml	4.195 ml	8.39 ml
10 mM	0.42 ml	2.098 ml	4.195 ml
50 mM	0.084 ml	0.42 ml	0.839 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

1-O-Hexyl-2,3,5-trimethylhydroquinone