S83468 |
trovirdine |
源叶(MedMol) | 99% |
- 产品描述: Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate. IC50 value: 7 nM Target: HIV-1 Trovirdine is currently in phase I clinical trials for potential use in thetreatment of AIDS.
- 靶点: HIV;HIVProtease
- 参考文献:
1. Zhang, H. et al. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethylthiazolyl thiourea derivatives trovirdine and MSC-127. 2. Cantrell, A.S. et al. Phenethylthiazolylthiourea (PETT) compounds as a newclass of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.
- 溶解性: DMSO : 100 mg/mL (296.52 mM; Need ultrasonic)
- 保存条件: 2-8℃
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 2.965 ml 14.826 ml 29.653 ml 5 mM 0.593 ml 2.965 ml 5.931 ml 10 mM 0.297 ml 1.483 ml 2.965 ml 50 mM 0.059 ml 0.297 ml 0.593 ml
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输入产品批号:
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)