S84700 |
Tavilermide |
源叶(MedMol) | 98% |
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- 产品描述: Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.
- 靶点: TrkA;Trkreceptor
- 体外研究:
Tavilermide (MIM-D3) is a tyrosine kinase TrkA receptor agonist, which can be used to treat dry eye.Tavilermide is a proteolytically stable, cyclic peptidomimetic that has been shown to be a partial TrkA receptor agonist. Tavilermide demonstrates activities similar to NGF (but does not bind to the p75NTR receptor) and can potentiate the effects of suboptimal concentrations of NGF
- 参考文献:
1. Meerovitch K, et al. Safety and efficacy of MIM-D3 ophthalmic solutions in a randomized, placebo-controlled Phase 2 clinical trial in patients with dry eye. Clin Ophthalmol. 2013;7:1275-85.
- 溶解性: Soluble in NH4OH、H2O
- 保存条件: -20℃
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 1.723 ml 8.613 ml 17.225 ml 5 mM 0.345 ml 1.723 ml 3.445 ml 10 mM 0.172 ml 0.861 ml 1.723 ml 50 mM 0.034 ml 0.172 ml 0.345 ml
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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)