S84796 |
Daun02 |
源叶(MedMol) | 98% |
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- 产品描述: Daun02 is a prodrug of the topoisomerase inhibitor Daunorubicin.
- 靶点: Topoisomerase;Daunorubicins/Doxorubicins;Topoisomerase
- 体内研究:
Daun02 is a good substrate for β-gal with Km and Vmax values of 0.37 mM and 8.6 μmol/min/mg protein. At a concentration of 10-5 M, Daun02 is 79% bound to plasma protein compares to 94% for Daunomycin
- 参考文献:
1. Koya E, et al. Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization. Nat Neurosci. 2009 Aug;12(8):1069-73. 2. Lehmann M, et al. Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test. Environ Mol Mutagen. 2004;43(4):250-7. 3. Farquhar D, et al. Suicide gene therapy using E. coli beta-galactosidase.Cancer Chemother Pharmacol. Cancer Chemother Pharmacol. 2002 Jul;50(1):65-70.
- 溶解性: Soluble in DMSO
- 保存条件: -20℃
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 1.13 ml 5.651 ml 11.302 ml 5 mM 0.226 ml 1.13 ml 2.26 ml 10 mM 0.113 ml 0.565 ml 1.13 ml 50 mM 0.023 ml 0.113 ml 0.226 ml
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输入产品批号:
本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)