货号	规格	价格	上海	北京	武汉	南京	购买数量
S85170-100mg	99%	￥700.00 S85170-100mg ￥700.00 现货	6 6	-	-	-

货号

规格

价格

上海

北京

武汉

南京

购买数量

S85170-100mg

99%

￥700.00

产品介绍

Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency

产品描述：

靶点：

Bacterial;SARS-CoV;Antibiotic;Antibacterial;Antibiotic

体内研究：

Clofoctol (175 mg/kg; i.p.; daily for 37 days) is capable of blocking tumour growth without apparent toxicity in a mouse model of human prostate cancer xenograft. Clofoctol (62.5 mg/kg; i.p.; twice) inhibits SARS-CoV-2 replication and lowers inflammation in lungs in mice with SARS-CoV-2 infection Animal Model: Male athymic nude mice (BALB/c, nu/nu-NCr) aged 4–6 weeks, human prostate cancer xenograft model Dosage: 175 mg/kg Administration: Intraperitoneal injection, daily for 37 days Result: Significantly inhibited PC3 tumour growth, tumour weight was also reduced by 60%.

参考文献：

1. Ghilardi PL, et al. Treatment of ear, nose and throat infections with clofoctol. Drugs Exp Clin Res. 1985;11(11):815-8. 2. Wang M, et al. Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer. Br J Pharmacol. 2014 Oct;171(19):4478-89. 3. Belouzard S, et al. Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice. PLoS Pathog. 2022 May 19;18(5):e1010498.

溶解性：

Soluble in DMSO

保存条件：

2-8℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.737 ml	13.686 ml	27.372 ml
5 mM	0.547 ml	2.737 ml	5.474 ml
10 mM	0.274 ml	1.369 ml	2.737 ml
50 mM	0.055 ml	0.274 ml	0.547 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

质检证书(COA)

输入产品批号：

如何获取质检证书(COA)?

请输入货号和一个与之匹配的批号。
例如:
批号：JS298415 货号：S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

计算重置

CLOFOCTOL