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Guanethidine Monosulfate 98%

Guanethidine Monosulfate

源叶(MedMol)
S86078
645-43-2
C10H24N4O4S
296.39
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶(MedMol) S86078-50mg 98% ¥168.00元 7 - - -
源叶(MedMol) S86078-100mg 98% ¥320.00元 3 - - -
源叶(MedMol) S86078-500mg 98% ¥800.00元 预计交期:2-3天 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Guanethidine sulfate (Guanethidine monosulfate) ia an antihypertensive agents. Guanethidine is also an adrenergic neurone blocking drug, enters noradrenergic nerve terminals by the neuronal amine carrier
产品描述: Guanethidine sulfate (Guanethidine monosulfate) ia an antihypertensive agents. Guanethidine is also an adrenergic neurone blocking drug, enters noradrenergic nerve terminals by the neuronal amine carrier
靶点: Norepinephrine
体内研究: Guanethidine (5-40 mg/kg; intraperitoneal injection; daily; for 4-28 days; male Wistar rats) treatment for 28 days by 40 mg/kg results in an incomplete sympathectomy accompanied by a partially irreversible hypersensitivity to noradrenaline, whereas 5 mg/kg does not induce histological or permanent haemodynamic changes
参考文献: 1. Mitchell JR, et al. Antagonism of the antihypertensive action of guanethidine sulfate by desipramine hydrochloride. JAMA. 1967 Dec 4;202(10):973-6. 2. Nielsen GD. Guanethidine induced sympathectomy in the adult rat. I. Functional effects following subacute administration. Acta Pharmacol Toxicol (Copenh). 1977 Sep;41(3):203-8. 3. Fabiani ME, et al. Inhibition of sympathetic noradrenergic transmission by guanabenz and guanethidine in rat isolated mesenteric artery: involvement of neuronal potassium channels. Pharmacol Res. 1996 Mar;33(3):171-80.
溶解性: Soluble  in  H2O
保存条件: 2-8℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 3.374 ml 16.87 ml 33.739 ml
5 mM 0.675 ml 3.374 ml 6.748 ml
10 mM 0.337 ml 1.687 ml 3.374 ml
50 mM 0.067 ml 0.337 ml 0.675 ml
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参考文献

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摩尔浓度计算器

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